A 2026 study in ACS Chemical Biology reveals that targeted protein degradation (TPD) technology eliminates not just individual target proteins, but entire native protein complexes — a "bystander degradation" phenomenon dictated entirely by protein-protein interaction context. Researchers at the MRC-PPU (University of Dundee) and Harvard demonstrated that the same molecular glue degraders driving clinical advances against leukemia and myeloma simultaneously codegraded multiple CK1α-SACK1 complex partners. The principle — that molecular context shapes every biological outcome — has direct implications for next-generation crop protection, biotech traits, and precision plant science.